NOVELTY – Producing kojic acid involves inoculating definite amount of fungal spores inoculum to the fermentation culture medium. The obtained crude fungal culture, after fermentation, is then tested to find out concentration of glycerol and biomass in it, along with the determination of pH. The obtained crude fungal culture is then centrifuged for fungal cell separation, where the leftover residue after centrifugation, is passed over affinity chromatography to obtain crude eluate. USE – Method for producing kojic acid (claimed). ADVANTAGE – The produced kojic acid is 99% pure. DETAILED DESCRIPTION – Producing kojic acid involves inoculating definite amount of fungal spores inoculum to the fermentation culture medium. The obtained crude fungal culture, after fermentation, is then tested to find out concentration of glycerol and biomass in it, along with the determination of pH. The obtained crude fungal culture is then centrifuged for fungal cell separation, where the leftover residue after centrifugation, is passed over affinity chromatography to obtain crude eluate. The obtained crude eluate is then treated with solvent for the extraction of kojic acid molecules, and then subjected to crystallization to obtain the finished product.

Main Application Field

D16 (Fermentation industry – including fermentation equipment, brewing, yeast production, production of pharmaceuticals and other chemicals by fermentation, microbiology, production of vaccines and antibodies, cell and tissue culture and genetic engineering.); E13 (Heterocyclics.)

INVENTORS:

ALEGRE RANULFO MONTE
COELHO RENATO SANO

424_GLICEROL

Patent number: BR201004121-A2

PATENT STATUS:

For information contact Inova Unicamp

FOR ADDITIONAL INFORMATION:

parcerias@inova.unicamp.br

+55 (19) 3521-5207 / 2607

This technology profile has been automatically generated.