Production of enantiomerically pure substituted benzodihydrofurans comprises aldehyde treatment for esters and acids fabrication, with recuperation of the catalyst
NOVELTY – The production of enantiometrically pure substituted benzodihydrofurans has processing based on a commercial aldehyde, for preparation of benzodihydrofuranic esters and acids. The catalyst (Dabco) permits asymmetric synthesis of the drug Efaroxan for use in Diabetes mellitus treatment, and is recuperated in the Baylis-Hillman adduct isolation process. EMBODIMENT – The stereogenic center present in Efaroxan is formed in the synthesis. USE – In physical chemistry.
Main Application Field
B02 (Fused ring heterocyclics.)
INVENTORS:
COELHO FERNANDO ANTONIO SANTOS
CARVALHO GABRIEL PINTO DE
131_EFAROXAN
Patent number: BR200603112-A
PATENT STATUS:
For information contact Inova Unicamp
FOR ADDITIONAL INFORMATION:
parcerias@inova.unicamp.br
+55 (19) 3521-5207 / 2607
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